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Talk to your pharmacist for more fore using this medication, tell your doctor or pharmacist your medical history, especially of: irregular heartbeat, liver disease, stomach/intestinal problems (e.g., recent abdominal surgery, ileus, swelling).Ondansetron may cause a side condition that affects the heart rhythm (QT prolongation). This medication may be taken with effects or without food. Hepatobiliary Liver enzyme abnormalities. Nausea and side vomiting side may persist throughout a pregnancy and in some cases, may be severe. . In fact, pregnant women with hyperemesis gravidarum who took ondansetron had side fewer miscarriages and higher live birth rates than those who didnt, according to the study. Zuplenz (ondansetron)." Strativa Pharmaceuticals, a Division of side Par Pharmaceuticals, Inc., Woodcliff Lake,. If you have side phenylketonuria (PKU you should know that taking the rapidly dissolving tablet form of zofran ondansetron (Zofran ODT) may increase your level of phenylalanine, which can be dangerous for you. SingleCare, a leading online service for prescription, dental, and vision discounts, has partnered with most major pharmacies around the country to help you save up to 80 percent off prescription costs. Ref Common (1 to 10 Sensation of warmth/flushing, bradycardia, hypotension, arrhythmias Uncommon (0.1 to 1 Chest pain with/without ST segment depression Rare (0.01.1 Transient ECG changes including QT interval prolongation (Torsade de Pointes angina /chest pain, vascular occlusive. For patients ages 12 and older, the dosage is the same as for adults. Zofran can be taken with or without food, and patients can continue their normal diet while taking Zofran. Brand name(S Zofran, medication Uses, how To effects Use, side Effects. Retrieved from.gov/pubmed/25450422 Fejzo,.S., MacGibbon,.W., Mullin,.M. Effect of a Single Dose.V. In 2011, the FDA issued a warning that ondansetron may increase the risk for abnormal changes in the electrical activity of the heart. Nagashree Seetharamu, an oncologist at the North Shore Long Island Jewish Cancer Institute at Lake Success in New York. Zofran (ondansetron)." Cerenex Pharmaceuticals, Research Triangle Pk,. Zofrans label advises doctors to perform heart monitoring of people who are taking the drug along with other medications that can also lead to QT prolongation or in patients with: Certain electrolyte abnormalities (such as low potassium or low magnesium). Ask your doctor or pharmacist if side you have form your doctor if your condition does not improve or if it worsens. Many people using this medication do not have serious side effects. This product may contain effects inactive ingredients, which can cause allergic reactions or other problems. Additionally, side Zofran was never approved to treat nausea and vomiting from morning sickness in pregnant women. Ref Nervous system Dizziness occurred during rapid IV administration. Signs and symptoms of arrhythmias linked to lengthened QT interval include: Unexplained fainting, seizures, drowning or near drowning. QT Prolongation Observed with Ondansetron: A Clinical Concern? The majority of the cases occurred in a post-anesthesia care unit or infusion center, but a Zofran overdose can also lead to serotonin syndrome. Generic name: side ondansetron - oral (on-DAN-se-tron).